Serological diagnosis of Helicobacter pylori and its role in the development of peptic ulcer in patients of the Cazin Health Center
Asmir Aldžić, Marija Radić, Emina Bajramović
SUMMARY
Helicobacter pylori is a bacterium that colonizes the human stomach and has been established as the causative agent of chronic superficial gastritis, chronic active gastritis, peptic ulcer disease, and gastric adenocarcinoma (Marshall et al., 1985). It has been proven that this bacterium can persist in the human body for many years, and whether its presence will manifest as symptomatic disease often depends on the patient’s immune system and overall physical condition. Helicobacter pylori, a Gram-negative bacterium, is of great clinical significance since more than 50% of the global population is infected. Approximately 90% of acute and chronic gastritis cases are caused by H. pylori, which is also present in 95% of duodenal ulcers and 70% of gastric ulcers.
This paper presents a two-year study on the identification of H. pylori using a non-invasive serological method at the Cazin Health Center. At this institution, we reviewed referrals and test results of all patients who were sent for H. pylori antigen detection. Upon admission, all patients reported abdominal pain, digestive difficulties, and excessive gastric acid secretion. In the laboratory of the Cazin Health Center, 2,751 antigen tests were performed on blood samples using the Mini Vidas analyzer.
10.57136/2303-7342.2025.18.18.59
- 1.01 - Izvorni naučni rad
